6 Best NR Supplements in 2026

“6 Best NR Supplements in 2026” is a collaborative post.

NR has been turning up everywhere in the wellness corner of the internet lately. Nicotinamide riboside, to give it its full name, is a form of vitamin B3, and it has quietly become one of the most talked about ingredients on the healthy ageing shelf.

Here is the plain version. Your cells rely on a coenzyme called NAD+ (nicotinamide adenine dinucleotide) to help convert food into cellular energy, and NR is what researchers call an NAD+ precursor, a building block your body can use to make more of it. That is why NR shows up in so many supplements aimed at cellular energy and cellular ageing. You will see NMN (nicotinamide mononucleotide) mentioned in the same breath, but it is a different precursor with its own separate research, so the two are not interchangeable.

One thing before the list. This is a comparison, not a ranking. There is no single winner here, because the right choice depends on what you want from a formula. Each brand is compared on:

• How much NR is in a serving, and in what form
• Whether the formula is NR on its own or NR alongside other actives
• Third party testing and certification, including whether the finished product is tested and not just the raw ingredient
• Label transparency, with exact amounts disclosed and no cheap fillers or additives
• How it fits into a daily routine

1. Elysium Health Basis, for a two-ingredient formula

Elysium Health takes a two-ingredient approach with Basis, which combines 250 mg of nicotinamide riboside with 50 mg of pterostilbene per two-capsule serving. Pterostilbene is a polyphenol related to resveratrol, and the brand positions the pairing around cellular ageing rather than NAD+ alone. Elysium cites a double-blind, randomised, placebo-controlled trial published in npj Aging and Mechanisms of Disease, in which NAD+ levels rose by an average of 40%. Worth reading that as a measured change in a blood marker rather than a promise about how you will feel.

The company was co-founded by Leonard Guarente, Ph.D., lists more than 25 scientists and clinicians as advisers, and Basis is NSF Certified for Sport, which the brand notes is the only independent third-party certification programme recognised by the United States Anti-Doping Agency. Two capsules in the morning, and the rest of the label is short: cellulose, hypromellose, magnesium stearate and silica.

2. Tru Niagen, for its research and testing record

Tru Niagen is built around Niagen, the patented nicotinamide riboside chloride made by ChromaDex. A single capsule provides 300 mg, keeping the formula and daily routine relatively simple.

What stands out is the paper trail. Niagen went through the FDA’s new dietary ingredient notification process twice, in 2015 and 2018, and was notified to the FDA as Generally Recognized as Safe in 2016. The company describes at least 19 internal and third-party tests across the ingredient and finished product, using laboratories including NSF and Alkemist Labs, and shoppers can enter the lot number from a bottle on the website to find the matching certificate of analysis. That gives the product a useful level of traceability.

3. Thorne NiaCel 400, for a higher-dose single capsule

Thorne’s NiaCel 400 provides 415 mg of nicotinamide riboside hydrogen malate in one capsule, along with 85 mg of betaine anhydrous, also known as TMG or trimethylglycine. It is also NSF Certified for Sport and gluten free.

The main difference here is the amount of NR in a single capsule compared with the other products covered in this list. More milligrams is not automatically better, though, so dose size is best treated as one comparison point rather than a reason to choose a product on its own.

4. Renue By Science Lipo NR, for a different delivery format

Renue By Science takes a different approach to delivery with Lipo NR. The product uses liposomal encapsulation, where the active sits inside a phospholipid structure that the company says helps protect it during delivery. Each vegetarian capsule contains 300 mg of NR.

The brand’s pages also list batch-level third-party testing, including test dates and the laboratory used, and state that products are made in ISO-certified and cGMP-certified facilities. They are also described as non-GMO and free from preservatives, artificial colours, flavours and sweeteners. Whether liposomal delivery makes a meaningful difference for NR specifically is still an open question, so it makes more sense to view it as a formulation preference than a settled advantage.

5. Nootropics Depot NR, for label transparency

Nootropics Depot keeps the formula straightforward. Each capsule provides 300 mg of nicotinamide riboside with no other active ingredients, and the brand publishes certificates of analysis by lot so shoppers can check the batch they have at home.

The company says every batch is tested at accredited third-party laboratories for potency, purity and contaminants before release. The capsules are also listed as lactose free, gluten free, non-GMO and vegan. For readers who prefer clear labels and batch-level documentation, this is one of the more transparent options.

6. Life Extension NAD+ Cell Regenerator, for a straightforward Niagen formula

Life Extension NAD+ Cell Regenerator provides 300 mg of Niagen nicotinamide riboside chloride in one vegetarian capsule a day. The range also includes a version that pairs NR with trans-resveratrol, quercetin and fisetin.

The product carries non-GMO and gluten-free labelling along with a ConsumerLab quality seal. Its appeal is fairly simple: a familiar single-capsule format built around a well-known branded form of NR, with the option of a more complex formula elsewhere in the range.

So how do they compare?

The clearest differences across the six are formulation, dose, testing and delivery format. Basis combines NR with pterostilbene, while Thorne includes betaine anhydrous. Life Extension also offers a separate formulation pairing NR with additional polyphenols. Tru Niagen and Nootropics Depot take a simpler approach, while Renue By Science stands out for its liposomal delivery format.

Testing is another useful separator. Basis and NiaCel 400 both carry NSF Certified for Sport, while Tru Niagen and Nootropics Depot make batch-level documentation available. Across the category, the most useful quality signals are disclosed ingredient amounts, finished-product testing, recognised certifications and accessible batch documentation.

A final and important note. NR research in humans is still fairly young, and nothing here treats, prevents or cures anything. Please consult a healthcare provider before starting any NAD+ precursor, particularly if you are pregnant, breastfeeding, taking medication or managing an existing health condition. There is no established safety data for NR in pregnancy or while nursing, so it is not a category to experiment with during either.

NR is one of the more closely studied ingredients in this corner of the supplement aisle, and these six show how differently it can be formulated. Comparing labels, testing and daily format is the most useful place to start.